The Meadow Valley Wash is a southern Nevada stream draining the Meadow Watershed that is bordered on three sides by the Great Basin Divide. The wash's Lincoln County head point is in the Wilson Creek Range, and the wash includes two upper confluences. Panaca is along the upper wash, and downstream of Caliente is the wash's confluence with its east fork. Just before the junction with the Muddy River, the wash flows from Lincoln County into northeastern Clark County. It flows into the Muddy in the Moapa Valley just west of Glendale adjacent to Interstate 15 approximately 40 miles (64 km) northeast of Las Vegas.